Motrin is an over-the-counter medication called a nonsteroidal anti-inflammatory drug (NSAID), designed to reduce fever, pain and swelling. Problems such as stomach ulcers and bleeding have been linked to NSAIDs like Motrin. Liver damage, aspirin-sensitive asthma, and fluid retention have also been linked to medication like Motrin.
Motrin is designed to treat general pain and swelling, as well as pain from osteoarthritis and rheumatoid arthritis. Osteoarthritis, or degenerative arthritis, is caused when the cartilage begins to wear down and decrease in bone joints. Osteoarthritis affects more than 20 million people in the U.S.
Osteoarthritis commonly affects the larger, weight bearing joints like hips, feet and hands, making it very difficult to maintain an active lifestyle once the pain begins to increase. Osteoarthritis is related to aging and repetitive use.
Motrin is used for patients suffering from rheumatoid arthritis, as well. Rheumatoid arthritis is an autoimmune disease (when the body attacks itself) that causes chronic inflammation of the joints. It can cause joint destruction and impaired mobility.
What are some important things I should know about Motrin?
Problems such as stomach ulcers and bleeding have been linked to NSAIDs like Motrin. Liver damage, aspirin-sensitive asthma, and fluid retention have also been linked to medications like Motrin, as have heart disease and strokes. Because of the risks of Motrin, taking the lowest possible dose for the shortest period of time is recommended.
Motrin is made in varying drug strengths suitable for infants to adults.
Motrin is often helpful in reducing pain and inflammation in many patients. However, it is important to be aware that side effects from Motrin can be serious and even deadly. Motrin can cause:
- heart attack
- stroke
- heart disease
- edema
- ulcers
- perforations of the intestines or stomach, which can be fatal
- dangerous allergic reactions
- an increase in symptoms in asthma patients
- kidney failure
- liver disease
- skin reactions
- pregnancy and birth complications
Patients taking Motrin should be aware of the harmful side effects, and report any symptoms to their doctors, including:
- unexplained weight gain
- rash
- lethargy
- jaundice
- allergic reaction
- nausea
- vomiting
- increase in blood pressure


