Ortho Prefest is designed to reduce the signs and symptoms of moderate to severe menopause in women and to prevent osteoporosis. However, Ortho Prefest, like other estrogen-containing drugs, can increase a woman’s risk of developing uterine cancer. People who should not use Ortho Prefest include women who are pregnant, have unusual bleeding that has not been evaluated by a doctor, have had certain types of cancer, have circulation problems, or have just had a baby and are breast feeding.
Signs and symptoms of moderate to severe menopause include hot flashes, which are sudden, intense episodes of heat and sweating, especially around the face and neck.
Osteoporosis is a natural thinning of bones as they age that make them more brittle and more likely to break. Women lose bone mass faster after menopause.
What are some important things I should know about Ortho Prefest?
Ortho Prefest, like other estrogen-containing drugs, can increase a woman’s risk of developing uterine cancer. Unusual vaginal bleeding is usually the first major sign of uterine cancer or other injuries. Women who have had their uterus removed will not be at risk of developing uterine cancer.
Ortho Prefest is for women experiencing moderate to severe signs and symptoms of menopause. Ortho Prefest can also help prevent osteoporosis.
- are pregnant
- have unevaluated, unusual vaginal bleeding
- have had certain types of cancer, including breast and uterine cancer
- have circulation problems like abnormal blood clotting conditions
- have just had a baby and are breast feeding
Ortho Prefest increases women’s risk of developing uterine cancer, breast cancer, gall bladder disease and abnormal blood clotting.
- nausea and vomiting
- breast tenderness or enlargement
- fluid retention
- skin discoloration, especially on the face
- irregular vaginal bleeding or spotting
- headache or migraine
- dizziness or fainting
- depression
- vaginal yeast infections








