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Vioxx: The Most Lucrative Drug Ever to Be Withdrawn from the Market

October 21st, 2008

Rofecoxib, more commonly known as Vioxx, was voluntarily withdrawn from the market by Merck on September 30, 2004. A widely accepted non-steroidal anti-inflammatory drug (NSAID), Vioxx was suspected by its producer to be related to several cardiovascular events, most commonly heart attacks and strokes, and other painful ailments.

Over its five year lifetime, Vioxx was prescribed to over 80 million people, and the year before it was removed from the market sales produced revenue of approximately $2.5 billion. It was one of the most lucrative drugs ever taken off the market by its manufacturer. Vioxx’s huge market success was a result of it aiding so many people in reducing or eliminating chronic or acute pain from osteoarthritis, dysmenorrhoea.

There is a lot of skepticism and controversy surrounding the release, studies, and eventual withdraw of Vioxx from the market. After its acceptance by the FDA as a “safe and effective” drug, later studies revealed that it may not actually be safe. The 12 month long Vioxx GI Outcomes Research (VIGOR) study materialized initial concerns about Vioxx and its relationship to cardiovascular problems. This study led to warning labels about Vioxx increasing the risk of heart attacks or strokes.

Any beliefs of openness and honesty that existed about Merck exposing possible risks were quickly halted when in just months after the first VIGOR study was published, more heart attacks caused by the drug were uncovered. The company’s rebuttal to the uncertainty of the accuracy of the study was that these additional heart attacks occurred after the predetermined time of the study had lapsed.

$4 Million Awarded to Indiana Family In Medical Malpractice Case

October 21st, 2008

Nearly $5 million was awarded to a Hammond, Indiana family in a medical malpractice case earlier this year. Roger Vuckovich, just twelve hours after being released from St. Catherine’s hospital in East Chicago, died of an adbdominal aortic aneurysm.

The abdominal aorta supplies blood to the abdomen, pelvis, and legs. Dr. Rajeev Sareen completed an emergency procedure on Mr. Vuckovich on December 22, 2001 and in the opinion of a jury in December of 2005, Dr. Sareen failed to complete a CT scan that could have shown the risk of Mr. Vuckovich’s aneurism. According to Barry Rooth, the Vuckovich’s attorney, Mr. Vuckovich was misdiagnosed and treated for having a kidney stone.

Vuckovich’s wife, Cynthia, received $2.2 million in the settlement and his three daughters each received $750,000. Rooth stated that he felt “heartened that the jury understood that the care required a CT under these circumstances.”

San Francisco Dog Bite Case Propels Dog Bite Law Forward

October 21st, 2008

The majority of dog bite incidents are not from unknown dogs; 77% of people bitten are bitten by a friend’s dog and half of all dog bites occur at the dog’s home. Since most of us do not keep mean pets, it is important to remember that certain precautions should be taken even around our sweet, loving four-legged family members.

In 33 states, the owner of a dog is completely responsible if his dogs hurts, or worse, kills a person. Many other states are in the process of passing similar bills. The very significant incident that propelled many of these legislations that hold dog owners accountable was a San Francisco, CA case in which a lawyer’s dogs attacked and killed Diane Whipple. Majorie Knoller and her husband were both sentenced to time in prison and hefty fines, and were held liable to Whipple’s death as well. This case of family pets attacking a neighbor reminds us to take special care when dealing with any animal, whether we know him or not.

Many studies have attempted to quantify the relationship between dog breed and chance of attack, although the reliability of these studies has been questioned. It is imperative that those without prior experience with dogs seek professional help in training their first furry friend. Some dogs may be predisposed to having aggressive personalities but good training can greatly reduce the risk of such aggressive traits becoming a reality. As well, a dog that is not prone to be violent may be if not handled and treated correctly. In general, we need to bear in mind that like us, dogs are not always predictable and we should always be mindful of their aggressive tendencies.

Horrific Car Accident Causes Death of Five Girls

October 21st, 2008

June 26, 2008. A horrific automobile crash caused the death of five high school girls from Penfield, NY. Bailey Goodman was driving with four friends to her beach house when she pulled into the left lane to pass another vehicle, pulled back into the right lane and then swerved back into the left lane, hitting a tractor-trailer truck head on. The SUV that Goodman was driving burst into flames upon impact, trapping and killing all five girls.

Investigations are still underway as to why the car burst into flames. It is unusual for automobiles to catch fire, and investigators are deciding whether something malfunctioned in the car, causing it to explode.
 
These five girls will be deeply missed by everyone who knew them. Elaborate ceremonies, memorials and scholarship funds have been dedicated to them and this accident serves as a reminder to everyone that accidents do happen and that we need to be as attentive as possible when driving.
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